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1

Structural insights into Alzheimer filament assembly pathways based on site-directed mutagenesis and S-glutathionylation of three-repeat neuronal Tau protein

Luca Dinoto, Michael A. Deture, Daniel L. Purich

Journal:

Microscopy Research and Technique

Année:

2005

Langue:

english

Fichier:

PDF, 420 KB

english, 2005

2

Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility

Naruhiko Sahara, Jada Lewis, Michael DeTure, Eileen McGowan, Dennis W. Dickson, Mike Hutton, Shu-Hui Yen

Journal:

Journal of Neurochemistry

Année:

2002

Langue:

english

Fichier:

PDF, 309 KB

english, 2002

3

Characterization and Localization of a Hybrid Non-ribosomal Peptide Synthetase and Polyketide Synthase Gene from the Toxic DinoflagellateKarenia brevis

Susanna López-Legentil, Bongkeun Song, Michael DeTure, Daniel G. Baden

Journal:

Marine Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 245 KB

english, 2010

4

Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression

Tadanori Hamano, Tania F. Gendron, Ena Causevic, Shu-Hui Yen, Wen-Lang Lin, Ciro Isidoro, Michael DeTure, Li-wen Ko

Journal:

European Journal of Neuroscience

Année:

2008

Langue:

english

Fichier:

PDF, 830 KB

english, 2008

5

Fibrillogenesis of Tau: Insights from Tau Missense Mutations in FTDP-17

Shu-Hui Yen, Michael Hutton, Michael DeTure, Li-Wen Ko, Parimala Nacharaju

Journal:

Brain Pathology

Année:

1999

Langue:

english

Fichier:

PDF, 291 KB

english, 1999

6

Cellular models for tau filament assembly

Li-wen Ko, Michael DeTure, Naruhiko Sahara, Rifki Chihab, Shu-Hui Yen

Journal:

Journal of Molecular Neuroscience

Année:

2002

Langue:

english

Fichier:

PDF, 90 KB

english, 2002

7

Missense tau mutations identified in FTDP-17 have a small effect on tau–microtubule interactions

Michael DeTure, Li-wen Ko, Samuel Yen, Parimala Nacharaju, Colin Easson, Jada Lewis, Marjon van Slegtenhorst, Michael Hutton, Shu-Hui Yen

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 756 KB

english, 2000

8

Evidence for independent mechanisms and a multiple-hit model of tau assembly

Michael DeTure, Brian Granger, Andrew Grover, Mike Hutton, Shu-Hui Yen

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 232 KB

english, 2006

9

Self-Assembly of the Brain MAP-2 Microtubule-Binding Region into Polymeric Structures Resembling Alzheimer Filaments

Edith Yi Zhang, Michael A. Deture, Michael R. Bubb, Tamara L. Caviston, Gregory W. Erdos, Scott D. Whittaker, Daniel L. Purich

Journal:

Biochemical and Biophysical Research Communications

Année:

1996

Langue:

english

Fichier:

PDF, 1.20 MB

english, 1996

10

Recent advances in experimental modeling of the assembly of tau filaments

Li-wen Ko, Michael DeTure, Naruhiko Sahara, Rifki Chihab, Irving E. Vega, Shu-Hui Yen

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2005

Langue:

english

Fichier:

PDF, 385 KB

english, 2005

11

tau Assembly in Inducible Transfectants Expressing Wild-Type or FTDP-17 tau

Michael DeTure, Li-wen Ko, Colin Easson, Shu-Hui Yen

Journal:

The American Journal of Pathology

Année:

2002

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2002

12

A novel tau mutation in exon 9 (1260V) causes a four-repeat tauopathy

Andrew Grover, Elisabet England, Mathew Baker, Naruhiko Sahara, Jennifer Adamson, Brian Granger, Henry Houlden, Ulla Passant, Shu-Hui Yen, Michael DeTure, Michael Hutton

Journal:

Experimental Neurology

Année:

2003

Langue:

english

Fichier:

PDF, 637 KB

english, 2003

13

S1-04-03 Cellular models for tauopathies

Shu-Hui Yen, Michael DeTure, Naruhiko Sahara, Li-wen Ko

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 169 KB

english, 2004

14

P2-133 Assembly of filamentous tau aggregates in conditional transfectants of human neuronal lineage that overproduce wild-type human brain tau in triple isoforms

Li-wen Ko, Toni Rush, Naruhiko Sahara, Jay S. Kersh, Michael DeTure, Wen-Lang Lin, Colin Easson, Yamicia D. Connor, Shu-Hui C. Yen

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 315 KB

english, 2004

15

Effects on splicing and protein function of three mutations in codon N296 of tau in vitro

Andrew Grover, Michael DeTure, Shu-Hui Yen, Mike Hutton

Journal:

Neuroscience Letters

Année:

2002

Langue:

english

Fichier:

PDF, 179 KB

english, 2002

16

Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration

Stephanie J. Adams, Richard J.P. Crook, Michael DeTure, Suzanne J. Randle, Amy E. Innes, Xin Z. Yu, Wen-Lang Lin, Brittany N. Dugger, Melinda McBride, Mike Hutton, Dennis W. Dickson, Eileen McGowan

Journal:

The American Journal of Pathology

Année:

2009

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2009

17

Characteristics of cytosolic hyperphosphorylated tau species in rTg4510 mouse brain

Naruhiko Sahara, Michael DeTure, Ebrahim Abdul-Shukkur, Søren Christensen, Dongcheul Kang, Josh Knight, Christiane Volbracht, Leonard Petrucelli, Shu-Hui Yen, Jada Lewis

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 58 KB

english, 2010

18

Regulation of the Hsp90 chaperone complex by HDAC6

Casey N. Cook, Judy Dunmore, Tania Gendron, Michael Deture, Leonard Petrucelli

Journal:

Alzheimer's & Dementia

Année:

2010

Langue:

english

Fichier:

PDF, 40 KB

english, 2010

19

Disulfide-Cross-Linked Tau and MAP2 Homodimers Readily Promote Microtubule Assembly

Luca Di Noto, Michael A. DeTure, Daniel L. Purich

Journal:

Molecular Cell Biology Research Communications

Année:

1999

Langue:

english

Fichier:

PDF, 196 KB

english, 1999

20

Induction of mutant tau expression in aged rTg4510 mice does not rapidly induce tauopathy

Cannon, Ashley D., DeTure, Michael, Knight, Joshua, Alosilla, Daniel, Dickson, Dennis W., Sahara, Naruhiko, Volbracht, Christiane, Lewis, Jada

Journal:

Alzheimer's & Dementia

Année:

2009

Langue:

english

Fichier:

PDF, 91 KB

english, 2009

21

A novel tau mutation, p.K317N, causes globular glial tauopathy

Tacik, Pawel, DeTure, Michael, Lin, Wen-Lang, Sanchez Contreras, Monica, Wojtas, Aleksandra, Hinkle, Kelly M., Fujioka, Shinsuke, Baker, Matthew C., Walton, Ronald L., Carlomagno, Yari, Brown, Patrici

Journal:

Acta Neuropathologica

Année:

2015

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2015

22

The involvement of the 5lipoxygenase pathway in tauopathy

Pratico, Domenico, Giannopoulos, Phillip, Li, Jian-Guo, Deture, Michael, Dickson, Dennis

Journal:

Alzheimer's & Dementia

Année:

2015

Langue:

english

Fichier:

PDF, 60 KB

english, 2015

23

Transmission of Soluble and Insoluble α-Synuclein to Mice

Jones, Daryl Rhys, Delenclos, Marion, Baine, AnnMarie T., DeTure, Michael, Murray, Melissa E., Dickson, Dennis W., McLean, Pamela J.

Journal:

Journal of Neuropathology and Experimental Neurology

Année:

2015

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2015

24

Impact of sex andAPOE4on cerebral amyloid angiopathy in Alzheimer’s disease

Shinohara, Mitsuru, Murray, Melissa E., Frank, Ryan D., Shinohara, Motoko, DeTure, Michael, Yamazaki, Yu, Tachibana, Masaya, Atagi, Yuka, Davis, Mary D., Liu, Chia-Chen, Zhao, Na, Painter, Meghan M.,

Journal:

Acta Neuropathologica

Année:

2016

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2016

25

TDP-43 FILAMENT ASSEMBLY IS INHIBITED BY HEAT SHOCK PROTEINS

DeTure, Michael, Carlomagno, Yari, Zhang, Yongjie, Davis, Mary, Lin, Wenlang, Petrucelli, Leonard

Journal:

Alzheimer's & Dementia

Année:

2014

Langue:

english

Fichier:

PDF, 83 KB

english, 2014

26

FTDP-17 with pick body-like inclusions associated with a novel tau mutation, p.E372G

Tacik, Pawel, DeTure, Michael A., Yari, Carlomagno, Lin, Wen-Lang, Murray, Melissa E., Baker, Matthew C., Josephs, Keith A., Boeve, Bradley F., Wszolek, Zbigniew K., Graff-Radford, Neill R., Parisi, J

Journal:

Brain Pathology

Année:

2016

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2016

27

Clinicopathologic heterogeneity in FTDP-17 due to MAPT p.P301L mutation, including a patient with globular glial tauopathy

Tacik, Pawel, Sanchez-Contreras, Monica, DeTure, Michael, Murray, Melissa E., Rademakers, Rosa, Ross, Owen A., Wszolek, Zbigniew K., Parisi, Joseph E., Knopman, David S., Petersen, Ronald C., Dickson,

Journal:

Neuropathology and Applied Neurobiology

Année:

2016

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2016

28

An acetylation-phosphorylation switch that regulates tau aggregation propensity and function

Carlomagno, Yari, Chung, Dah-eun Chloe, Yue, Mei, Castanedes-Casey, Monica, Madden, Benjamin J., Dunmore, Judy, Tong, Jimei, DeTure, Michael, Dickson, Dennis W., Petrucelli, Leonard, Cook, Casey

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 2.94 MB

english, 2017

29

GENETIC MUTATIONS IN MAPT AND SIGNIFICANT VARIABILITY IN TAU PROTEIN MODIFICATIONS INDICATE THE EXISTANCE OF A WIDE ARRAY OF STRAINS WITHIN AND ACROSS PRIMARY AND SECONDARY TAUOPATHIES

DeTure, Michael, Tacik, Pawel, Kouri, Naomi, Carlomagno, Yari, Ross, Kelly, Murray, Melissa E., Dickson, Dennis W.

Journal:

Alzheimer's & Dementia

Année:

2017

Langue:

english

Fichier:

PDF, 160 KB

english, 2017

30

Transmission of Soluble and Insoluble α-Synuclein to Mice

Jones, Daryl Rhys, Delenclos, Marion, Baine, AnnMarie T., DeTure, Michael, Murray, Melissa E., Dickson, Dennis W., McLean, Pamela J.

Journal:

Journal of Neuropathology and Experimental Neurology

Année:

2015

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2015

31

Relationships between lewy and tau pathologies in 375 consecutive non-Alzheimer's olfactory bulbs

Kasanuki, Koji, Ross, Owen A., DeTure, Michael A., Walton, Ronald L., Sanchez-Contreras, Monica, Koga, Shunsuke, Murray, Melissa E., Rademakers, Rosa, Dickson, Dennis W.

Journal:

Movement Disorders

Année:

2018

Langue:

english

Fichier:

PDF, 166 KB

english, 2018

32

Assembly of filamentous tau aggregates in human neuronal cells

Ko, Li-Wen, Rush, Toni, Sahara, Naruhiko, Kersh, Jay S., Easson, Colin, DeTure, Michael, Lin, Wen-Lang, Connor, Yamicia D., Yen, Shu-Hui C.

Journal:

Journal of Alzheimer's Disease

Année:

2005

Langue:

english

Fichier:

PDF, 222 KB

english, 2005

33

Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments

Adams, Stephanie J., DeTure, Michael A., McBride, Melinda, Dickson, Dennis W., Petrucelli, Leonard, Ferreira, Sérgio Teixeira

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2010

34

Casein Kinase II Induced Polymerization of Soluble TDP-43 into Filaments Is Inhibited by Heat Shock Proteins

Carlomagno, Yari, Zhang, Yongjie, Davis, Mary, Lin, Wen-Lang, Cook, Casey, Dunmore, Judy, Tay, William, Menkosky, Kyle, Cao, Xiangkun, Petrucelli, Leonard, DeTure, Michael, Kahle, Philipp J.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 5.91 MB

english, 2014

35

rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies

Croft, Cara L., Cruz, Pedro E., Ryu, Daniel H., Ceballos-Diaz, Carolina, Strang, Kevin H., Woody, Brittany M., Lin, Wen-Lang, Deture, Michael, Rodríguez-Lebrón, Edgardo, Dickson, Dennis W., Chakrabart

Journal:

Journal of Experimental Medicine

Année:

2019

Langue:

english

Fichier:

PDF, 4.59 MB

english, 2019

36

Tau exhibits unique seeding properties in globular glial tauopathy

Chung, Dah-eun Chloe, Carlomagno, Yari, Cook, Casey N., Jansen-West, Karen, Daughrity, Lillian, Lewis-Tuffin, Laura J., Castanedes-Casey, Monica, DeTure, Michael, Dickson, Dennis W., Petrucelli, Leona

Journal:

Acta Neuropathologica Communications

Année:

2019

Langue:

english

Fichier:

PDF, 6.22 MB

english, 2019

37

The neuropathological diagnosis of Alzheimer’s disease

DeTure, Michael A., Dickson, Dennis W.

Journal:

Molecular Neurodegeneration

Année:

2019

Langue:

english

Fichier:

PDF, 5.43 MB

english, 2019

38

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Duong, Duc M., Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Pe

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 8.39 MB

english, 2020

39

Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

Chitu, Violeta, Biundo, Fabrizio, Shlager, Gabriel G.L., Park, Eun S., Wang, Ping, Gulinello, Maria E., Gokhan, ÅÃ¶len, Ketchum, Harmony C., Saha, Kusumika, DeTure, Michael A., Dickson, Dennis W., Ws

Journal:

Année:

2020

Fichier:

PDF, 6.85 MB

2020

40

Î±-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species

Morgan, Sophie A., Lavenir, Isabelle, Fan, Juan, Masuda-Suzukake, Masami, Passarella, Daniela, DeTure, Michael A., Dickson, Dennis W., Ghetti, Bernardino, Goedert, Michel

Journal:

Journal of Biological Chemistry

Année:

2020

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2020

41

Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimerâs disease

Abskharon, Romany, Seidler, Paul Matthew, Sawaya, Michael R., Cascio, Duilio, Yang, Tianxiao P., Philipp, Stephan, Williams, Christopher Kazu, Newell, Kathy L., Ghetti, Bernardino, DeTure, Michael A.,

Journal:

Journal of Biological Chemistry

Année:

2020

Fichier:

PDF, 4.20 MB

2020

42

Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease

Liu, ChiaâChen, Yamazaki, Yu, Heckman, Michael G., Martens, Yuka A., Jia, Lin, Yamazaki, Akari, Diehl, Nancy N., Zhao, Jing, Zhao, Na, DeTure, Michael, Davis, Mary D., Felton, Lindsey M., Qiao, Wenh

Journal:

Alzheimer's & Dementia

Année:

2020

Fichier:

PDF, 460 KB

2020

43

Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology

Hou, Xu, Watzlawik, Jens O., Cook, Casey, Liu, ChiaâChen, Kang, Silvia S., Lin, WenâLang, DeTure, Michael, Heckman, Michael G., Diehl, Nancy N., AlâShaikh, Fadi S. Hanna, Walton, Ronald L., Ross

Journal:

Alzheimer's & Dementia

Année:

2020

Fichier:

PDF, 8.62 MB

2020

44

Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples

Watzlawik, Jens O., Hou, Xu, Truban, Dominika, Ramnarine, Chloe, Barodia, Sandeep K., Gendron, Tania F., Heckman, Michael G., DeTure, Michael, Siuda, Joanna, Wszolek, Zbigniew K., Scherzer, Clemens R.

Journal:

Année:

2020

Fichier:

PDF, 3.45 MB

2020